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CD70 抗体

This anti-CD70 antibody is a 大鼠 单克隆 antibody detecting CD70 in FACS 和 Func. Suitable for 小鼠.
产品编号 ABIN2567914
发货至: 中国

Quick Overview for CD70 抗体 (ABIN2567914)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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小鼠

宿主

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  • 1
大鼠

克隆类型

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单克隆

标记

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This CD70 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

FR70
  • 特异性

    The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily. CD70 is the ligand for CD27 and is expressed on dendritic cells, activated B cell, and a subset of activated T cells at lower levels. Its main role is in regulating B cell activation and immunoglobulin synthesis. CD70 expressing cells are able to co-stimulate T cell proliferation and upregulate cytokine production. The FR70 antibody is reported to block the binding of CD70 to CD27.

    基因ID

    21948

    UniProt

    O55237

    途径

    Cancer Immune Checkpoints
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